CONTACT Platform v2.0
☾
?
Sign in
00CHAT
01BUILD MONOGRAPHNEW
02TRIAL AUTOPSY
02+TRIAL COUNTERFACTUALNEW
03COMPETITIVE THREAT
04REFORMULATION
05INTELLIGENCE
06TECH TRANSFER
07PRICE BENCHMARK
08CTD ASSISTANT
09PROJECTS
★PLANS & PRICING

Build Your PureMonograph

Generate a complete pharmaceutical monograph for a novel molecule from scratch — QTPP, mechanism, formulation, stability, regulatory, IP, risk register. For re-engineering an existing molecule, use Reformulation.

Inspired by Rosie — AI-designed personalized neoantigen cancer vaccine for a dog
10
Scientific dimensions
NOVEL DESIGN
REDESIGN / CONVERT
IDEA INTAKEPlain English · AI asks clarifying questions
Format: GENE MUTATION, comma-separated. Each mutation must cite either a real MHC-I binding score or 'no validated source located'.
10 dimensions · CTD-ready · Uses credits (extra cost)
A — TARGET & DISEASE BIOLOGY
B — 10-AREA SCIENTIFIC ANALYSIS
C — CLARIFICATION QUESTIONS

Answer to unlock full monograph generation.

D — COST ANALYSIS
E — PURE MONOGRAPH

Trial Autopsy v2

Search literature and registries, pick a study, run a 6-lens autopsy, annotate findings.

6
Diagnostic lenses
RAG-grounded across 19 sources · single Grok-4 call · annotation feeds back into the dataset
1 · SEARCH
Fans out across 19 RAG sources (~3-8s)

Trial Counterfactual

Premium biostat + regulatory consultation. Project HR and success probability against a 20–50 trial historical cohort, then apply ranked design changes with quantified probability lift — one click to regenerate.

20–50
Historical trial peers
World-class design review · dissent on every call · one-click apply & regenerate
1 · PLANNED TRIAL DESIGN
Deep CT.gov cohort (20–50 peers) + PubMed/FDA · dissent-calibrated · ~60–90s

Competitive Threat Intelligence

Full competitive brief — patent landscape, differentiation gaps, approval timeline, commercial threat score, strategic response playbook.

5
Strategic dimensions
Citeline charges $50K–$80K per report
COMPETITIVE TARGET
Patent · clinical · commercial · strategic response
COMPETITIVE LANDSCAPE
THREAT ASSESSMENT
STRATEGIC PLAYBOOK

Reformulation Lab

Re-engineer existing molecules. Take a molecule you already know and design one new aspect: dosage form (tablet → patch), strength (5mg → 10mg), release profile (IR → ER), or route (oral → injectable). For brand-new molecules, use Build Monograph.

5
Pipeline stages
Senior med-chem consultant: $500/hr × 1 week = $20K+
DESIGN INPUT
CLIENT DATA + TRIAL HISTORYOptional — AI weights heavily
5 stages · ~30 seconds · real AI calls
A — DISEASE INTELLIGENCE
B — DATABASE SWEEP
C — CLIENT CONTEXT
D — INTERROGATION

Answer all questions to continue.

E — DESIGN OUTPUT
CONTACT
×
TERMS & CONDITIONS
×

LAST UPDATED 2026-04-16

1. Service

Pure Monograph is an AI-assisted research tool that generates draft pharmaceutical regulatory, CMC, and design documentation for professional users.

2. No regulatory or medical advice

Outputs are experimental. You must independently verify every claim, specification, citation, and regulatory reference before clinical, manufacturing, or submission use. We make no warranty of fitness for any regulated purpose.

3. Your content

You retain ownership of documents you upload. You grant us a limited, non-exclusive licence to process them solely to produce your outputs. We do not train public models on your private uploads.

4. Acceptable use

Do not use the service to generate content for unauthorised clinical trials, to evade regulatory review, to infringe third-party IP, or in violation of applicable export controls.

5. Subscriptions & credits

Paid plans renew monthly or annually at the price shown at purchase. Per-credit purchases are non-refundable once consumed. Subscriptions may be cancelled in Settings; access continues until the end of the paid period.

6. Liability

To the maximum extent permitted by law, aggregate liability is capped at the fees you paid in the preceding 12 months. We are not liable for indirect, consequential, regulatory, or clinical-outcome damages.

7. Governing law

These Terms are governed by the laws of British Columbia, Canada. Disputes will be resolved in the courts of Vancouver, BC.

8. Contact

Questions: [email protected].

PRIVACY POLICY
×

LAST UPDATED 2026-04-16

1. What we collect

Account data (name, email, plan), authentication metadata, usage logs (queries, credits consumed), and documents you upload for analysis.

2. How we use it

To run the service, meter usage, deliver outputs you request, send transactional 2FA codes, and improve reliability. We do not sell personal data.

3. Processors

We share the minimum necessary data with: Anthropic and xAI (model inference), Stripe (payments), Brevo (transactional email), Railway and Cloudflare (hosting and edge network). Each is contractually bound to confidentiality and data-protection terms.

4. Uploaded documents

Private uploads are processed to produce your output and retained only for your session context. They are not used to train third-party public models.

5. Retention

Account records are retained while your account is active and for up to 24 months after closure for audit, billing, and fraud-prevention purposes. You may request earlier deletion by email.

6. Your rights

GDPR/UK-GDPR/CCPA residents may request access, correction, deletion, or portability of their data by emailing [email protected].

7. Security

TLS in transit, encrypted storage at rest with the hosting provider, scoped API keys, and bcrypt password hashing. No system is perfectly secure — we will notify affected users promptly in the event of a material breach.

8. Contact

Privacy questions: [email protected]. Controller: Pure Monograph, Vancouver, BC.

Pharmaceutical AI Chat

Ask anything — CMC, regulatory, formulation, clinical, IP. Answers are pharmaceutical-specialist grade. Clarifying questions intercept complex queries before answering.

∞
Query depth

Pharmaceutical Intelligence

Market analysis, pipeline intelligence, competitive landscapes, regulatory trends, patent analysis, and deal flow. Select a focus and enter your topic.

9
Focus areas
INTELLIGENCE QUERY
2,000–4,000 word analyst-grade brief

Tech Transfer Package

Generate a complete pharmaceutical tech transfer package. Select scope, enter molecule details, and the AI produces a full TT document — process description, analytical methods, specifications, stability, and risk register.

16
Scope options
MOLECULE & PRODUCT DETAILS
TRANSFER SCOPESelect all that apply
Full pharmaceutical tech transfer document · Uses credits (extra cost)
PHASE 1 — PROCESS & MANUFACTURING
PHASE 2 — ANALYTICAL & SPECIFICATIONS
PHASE 3 — STABILITY, RISK & REGULATORY

Price Benchmark

Answers two questions. What does my product cost in a specific market? — see every brand, biosimilar, and generic already priced in that country, side-by-side. How does my product benchmark globally? — compare it to similar molecules across the markets you are targeting. Every number is traceable to a source URL or flagged UNVERIFIED — no fabricated data.

8
Public sources
Covers brand originators, authorised generics, biosimilars, and unbranded generics · 7-sheet xlsx export
MARKET ENTRYSame molecule, different brands, in ONE country
Black button = instant simulation (recommended) · Grey = live scrapers (auto-falls back to simulation if empty)

CTD Assistant

Expert Q&A on CTD structure, CMC requirements, ICH guidelines, and regulatory submission strategy. This module answers questions — it does not fabricate CTD documents. Real CTDs require actual batch data, analytical validation, and clinical results.

M1–5
CTD modules covered
⚠ EXPERT Q&A ONLY — Submission-ready CTD documents require your actual batch records, analytical validation data, stability results, and clinical data. This assistant guides structure and requirements — it does not generate submission documents from thin air.
SETTINGS ×
Account
FREE PLAN
Subscription
Manage billing and plan
Scientist Profile
Role
Tunes AI tone & confidence scoring
Therapeutic Focus
Pre-fill module defaults
Primary Jurisdiction
Regulatory defaults & confidence tuning
Company Type
Context for examples & next steps
Platform Preferences
Pipeline Stage
Depth of regulatory detail
Output Settings
CEO / Learning Mode
Plain-English explanations alongside technical output
Verbose Citations
Include full guideline references in every output
Typewriter Effect
Animate text as it generates
Risk Flag Alerts
Highlight regulatory and scientific risks in outputs
API & Integrations
API Access
Pro and Enterprise plans only
AI Keys (BYOK)
Use your own xAI (xai-…) or Anthropic (sk-ant-…) key. Stored encrypted server-side — never in your browser.
Export Format
Default download format
Account Actions

Plans & Pricing

Pay for access. Pay for what you generate. A subscription unlocks modules; heavy deliverables run on your own Grok API key. Upgrade or downgrade any time.

FREE
$0
forever
5 queries / day
Chat + Intelligence taste
Upgrade to unlock modules
Heavy deliverables need your API key
Community support
BASIC
$199
/ month
billed monthly
15 queries / day
All core modules
Heavy modules: your API key
PDF + Word export
Email support
1 user seat
GET STARTED →
PRO
$499
/ month
billed monthly
50 queries / day
All modules + Formulation Lab
Heavy modules: your API key
Priority generation queue
API access (beta)
Up to 3 seats
UPGRADE TO PRO →
ENTERPRISE
$1,499
/ month
billed monthly
100 queries / day
Full CTD + Tech Transfer
White-label option
Dedicated API
SSO + audit logs
Unlimited seats
GET ENTERPRISE →
All plans billed monthly. Cancel any time. Secure payment via Stripe.
Terms & Conditions · Privacy Policy · Contact
7-day free trial · Secure Stripe checkout

Projects

One row per project. Open Chat jumps straight to your most recent thread (creating one if none exist yet). Use Research above when you need per-thread management.

0
Projects